Genome3D
is a model-view framework for displaying genomic and
epigenomic data within a three-dimensional physical
model of the human genome. In this framework, the
model of the physical genome implicitly contains all
levels of structure and hierarchy, and provides an
underlying platform for integrating multi-scale
structural and genomic information within three
dimensions. The viewer is a Microsoft Windows based
software designed to display data from multiple scales
and uses a hierarchical model of the relative positions
of all nucleotide atoms in the cell nucleus, i.e., the
physical genome. With Genome3D, multi-resolution data
can be interactively explored to uncover complex and new
structural relationships. Genome3D is designed with a
hierarchical architecture that establishes methods for
incorporating new data of varying resolutions, and allows
for user-defined annotations. The viewer can also be
used to display other 3D genome models as long as they
are specified in Genome3D format. A platform independent,
fast response, cloud ready viewer prototype has also been
developed to employ game engine to visualize 3D genome structure.
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